THE DEFINITIVE GUIDE TO LSD CRYSTAL

During the LSD-sure crystal construction, the side chain of the lid residue L209EL2 types substantial hydrophobic contacts with both of those LSD and encompassing residues in TMs III, IV, and V (Figure 4C). If the lid moved apart to expose the binding pocket in simulation, several of those contacts broke. We So hypothesized that L209EL2 acts being